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Consult the. Mitochondrial genetic disorders (mtDNA nucleotide positions refer to the L-chain, and are taken from the "standard Cambridge" sequence) Rearrangements (large-scale partial deletions and duplications) Chronic progressive external ophthalmoplegia (CPEO) Kearn's Sayre syndrome Diabetes and deafness Pearson marrow-pancreas syndrome Sporadic tubulopathy Point mutations Protein-encoding genes LHON (G11778A, T14484C, G3460A) NARPLeigh syndrome (T8993GC) tRNA genes MELAS (A3243G, T3271C, A3251G) MERRF (A8344G, T8356C) CPEO (A3243G, T4274C) Myopathy (T14709C, Al 2320G) Cardiomyopathy (A3243G, A4269G, A4300G) Diabetes and deafness (A3243G, C12258A) Encephalomyopathy (G1606A, T10010C) rRNA genes Non-syndromic sensorineural deafness (A7445G) Aminoglycoside induced non-syndromic deafness (A1555G) Nuclear genetic disorders Disorders of mtDNA maintenance Autosomal dominant progressive external ophthalmoplegia (with 2В multiple mtDNA deletions) Mutations in adenine nucleotide translocator (ANT1) Mutations in DNA polymerase y (POLG) Mutations in Twinkle helicase (ClOorfl) Mitochondrial neuro-gastrointestinal encephalomyopathy (with 2В multiple mtDNA deletions) Mutations in thymidine phosphorylase (TP) Myopathy with mtDNA depletion Mutations in thymidine kinase (TK2) Encephalopathy with liver failure Mutations in option trading paper kinase (DGK) Inheritance pattern S S S S S M M M M M M M M M M M Inheritance pattern AD AD or AR AD AR AR AR Page Forex trading club london пTable 1 (Continued) Primary disorders of the respiratory chain Leigh syndrome Complex I deficiency в mutations in complex I subunits (NDUFS2,4,7,8 a n d NDUFV1) Complex II forex broker paypal в mutations in complex II flavoprotein subunit (SDHA) Binary options brokers united states and myoclonic epilepsy Complex I deficiency в mutations in complex I subunit (NDUFV1) Cardioencephalomyopathy Complex I deficiency в mutations in complex I subunit Binary options brokers united states Optic atrophy and ataxia Complex II deficiency в mutations in complex II flavoprotein s u b u binary options brokers united states i t (SDHA) Disorders of mitochondrial protein import Dystonia-deafness Mutations in deafness-dystonia protein DDP1 (TIMM8A) Disorders of assembly of the respiratory chain AR AR AR AR AD XLR AR AR Binary options brokers united states AR AR AR Leigh syndrome Complex IV deficiency protein (SURFI) Fx cci rsi IV deficiency protein (COX10) Cardioencephalomyopathy Complex IV deficiency в mutations in COX assembly в mutations in COX assembly в mutations in COX assembly protein (SC02) Hepatic failure and encephalopathy Complex IV deficiency в mutations in COX assembly protein (SCOl) Complex IV deficiency в mutations in protein affecting COX mRNA stability (LRPPRC) Tubulopathy encephalopathy and liver failure Complex III deficiency в mutations in complex III assembly (BCS1L) (AD autosomal dominant, AR autosomal recessive, M maternal, S sporadic, XLR X linked recessive) Whilst this general rule is helpful, it can only be binary options bonus no deposit of the explanation.
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